You may or may not be aware that VMware have always stated a supported maximum number of virtual machines per host in HA & DRS clusters. Because the number changed significantly between an 8 & 9 node cluster this was often used as a contributing factor for sizing.
However, as of vSphere 4.1 the limits have been increased and are no longer linked to the cluster size.
Below are the details for v4.0, 4.0 U1 & 4.1
VM’s per host in an HA cluster with 8 or < hosts (4.0 = 100) (4.0 U1 = 160) (4.1 = 320)
VM’s per host in an HA cluster with 9 or > hosts (4.0 = 40) (4.0 U1 = 40) (4.1 = 320)
VM’s per host in a DRS cluster (4.0 & 4.0 U1 = 256)
Maximum VM’s in an HA/DRS cluster (Powered on) (4.0 & 4.0U1 = 1280) (4.1 = 3000)